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Ms. Toad

(38,422 posts)
4. They are all but certain that the same clotting disorder is caused
Fri Apr 16, 2021, 08:44 PM
Apr 2021

by Astra Zeneca (which uses the same adenovirus vector). (Caused, not correlation)

The clotting disorder is strikingly similar to one known to be caused by heparin, and a mechanism has been proposed that explains the similarity between the two.

“Causality is more of a journey to certainty than a binary decision,” says Anthony Cox, an expert on pharmacovigilance at the University of Birmingham. But faced with accumulating cases, the European Medicines Agency (EMA), which had been careful not to point fingers, acknowledged on 7 April “a probable causal association” between the syndrome and the vaccine, recently named Vaxzevria.
. . .

On Friday, some of the first researchers to describe the condition published their observations in The New England Journal of Medicine. One team describes 11 patients in Germany and Austria; the other has observations on five patients in Norway. Both teams found the patients had unusual antibodies that trigger clotting reactions, which use up the body’s platelets and can block blood vessels, leading to potentially deadly strokes or embolisms.

The symptoms resemble a rare reaction to the drug heparin, called heparin-induced thrombocytopenia (HIT), in which the immune system makes antibodies to a complex of heparin and a protein called platelet factor 4 (PF4), triggering platelets to form dangerous clots throughout the body. Sickened vaccine recipients also had antibodies to PF4, the researchers found.


https://www.sciencemag.org/news/2021/04/hard-choices-emerge-link-between-astrazeneca-vaccine-and-rare-clotting-disorder-becomes

Recommendations

0 members have recommended this reply (displayed in chronological order):

I'm skeptical that these clots qazplm135 Apr 2021 #1
see this for a more robust discussion Celerity Apr 2021 #2
They are all but certain that the same clotting disorder is caused Ms. Toad Apr 2021 #4
VAERS data released today by CDC show 795 reports of blood clotting disorders womanofthehills Apr 2021 #12
Yes Sgent Apr 2021 #20
The concern isn't the general random formation of clots. Ms. Toad Apr 2021 #21
I got the Johnson & Johnson vaccine three weeks ago, PoindexterOglethorpe Apr 2021 #3
Same Calculating Apr 2021 #5
The US purchased enough of the two mRNA vaccines to vaccinate the entire population. Ms. Toad Apr 2021 #7
That's not really the point. Ms. Toad Apr 2021 #6
with J and J qazplm135 Apr 2021 #8
This particular clotting disorder is incredibly rare - Ms. Toad Apr 2021 #10
That's not what I've been reading qazplm135 Apr 2021 #11
The numbers of blood clotting disorders in J & J keeps growing womanofthehills Apr 2021 #13
It's not just blood clotting - it's blood clots with a low platelet count womanofthehills Apr 2021 #16
The mRNA vaccines are scientifically remarkable, and have such promise for all kinds BComplex Apr 2021 #9
They are amazing on one level, but too many people are dying from them - according to VAERS reports womanofthehills Apr 2021 #14
Correlation does not prove causation. speak easy Apr 2021 #17
No, that's wrong. The FDA has investigated ALL those deaths and found NO EVIDENCE they were caused pnwmom Apr 2021 #22
You have to realize that just because someone died after getting a vaccine, it doesn't mean vaccine LisaL Apr 2021 #23
Pfizer/BioNTech refused to take Warp Speed money. speak easy Apr 2021 #15
but Moderna got $1.5 billion from Warp Speed and Astra Zenica got $1.2 billion from Warp Speed womanofthehills Apr 2021 #18
mRNA vaccines would exist with U.S. investment. speak easy Apr 2021 #19
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