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In reply to the discussion: Trader Joes will no longer require masks for fully vaccinated people!! [View all]womanofthehills
(8,891 posts)Your own individual immune system. From Forbes-
The second consideration, which Ive already written about at length in my viral variation series for Forbes, is that the new SARS-CoV-2 variants are proving to be more difficult to neutralize than the original wild-type virus that emerged out of Wuhan, China. Several studies have already documented how the efficacy of the first generation of Covid-19 vaccineseven at their most potent, in the days following immunizationfalters against the B.1.351 variant in particular, remaining protective but not as much as before. The predictive model echoed this, showing that the variants pose a greater threat to vaccines with a lower initial efficacy against the wild-type virus. If the initial efficacy of a vaccine is around 70 percent, for example, and the neutralizing titers of the vaccine are reduced five-fold due to a new variant, the researchers predict efficacy will fall to just 25 percent.
This brings up a third and final considerationthat not all vaccines are created equal. While the correlation between initial efficacy and duration of protection is consistent across all the vaccines, their individual neutralizing antibody titers varied widely. The Pfizer and Moderna mRNA vaccines performed the strongest, with an initial efficacy of 95 percent that didnt drop to 50 percent until around day 200. By contrast, the Johnson & Johnson and AstraZeneca adenovirus vaccines, which had an initial efficacy of 67 and 62 percent respectively, reached the 50 percent mark around day 50. At the far end of the spectrum was the Sinopharm vaccine, which had an initial efficacy of 50 percent in the first place and, within the same amount of time, offered next to no protection at all
https://www.forbes.com/sites/williamhaseltine/2021/03/25/modeling-study-predicts-immune-protection-may-vary-for-different-covid-19-vaccines/?sh=78ac83705dd2