General Discussion
In reply to the discussion: Covid infections are up by 68%, over the past two weeks, in my county [View all]wnylib
(25,956 posts)I only used the Plague as an example of the Darwinian aspect of diseases that a population has had no prior exposure to. The ones capable of biologically surviving it (leaving out for the moment those whose genetics could survive it but whose living circumstances, like malnutrition, etc. weaken them) will have descendants who inherit whatever genetic immune strength against the disease they have. Those who aren't able to fight off the disease and survive will have fewer, or no descendants. So in a few generations, the disease will be less able to get a foothold in previously exposed populations. Unless it is caused by a virus that mutates enough to get past the immune system in previously exposed people, which the covid coronavirus seems able to do.
I've read that some people who have had a definite exposure to covid lasting more than a few minutes don't test positive and seem to be immune. That, plus the variations in the degree of illness and recovery make me wonder about a genetic factor in who gets a really bad case or who gets long covid. I know that specific comorbidities are factors, but what about the variations in people who do not have those issues?
I have always, since childhood, been more susceptible to viral infections than most people. I used to joke that if a virus showed up on the opposite side of town from me at midnight, it would find me by morning. And, it would cause a worse case of illness in me than in most people. If I get a cold or flu, it always, without exception, turns into viral bronchitis that triggers multiple asthma attacks until I get over it with help from a Z Pak.
Couple questions since you seem to be knowledgeable on the covid coronavirus. Hypertension is a factor in being vulnerable to a serious case of covid. But I take Losartan which controls it well. I read that people who take Losartan have a 40% reduced chance of a bad covid case if they do get it since Losartan is an ACE inhibitor. True that Losartan reduces the seriousness of an infection?
What about people with an autoimmune disorder, but are not taking steroids for it? Would the inflammation from an autoimmune disorder make it more likely that, IF infected, it could require hospitalization? Diabetics are vulnerable and that is an autoimmune disorder. What about other autoimmune conditions like rheumatoid arthritis or Hasimoto's?