General Discussion
In reply to the discussion: Antidepressants to treat grief? Psychiatry panelists with ties to drug industry say yes [View all]phleshdef
(11,936 posts)He also said that the way the theory is stated is wrong, thus not declaring the entire theory wrong. And he did acknowledge neuron related chemicals playing a role in setting the stage for depression.
This article from Harvard Medical School pretty much makes a similar point but elaborates.
"Its often said that depression results from a chemical imbalance, but that figure of speech doesnt capture how complex the disease is. Research suggests that depression doesnt spring from simply having too much or too little of certain brain chemicals. Rather, depression has many possible causes, including faulty mood regulation by the brain, genetic vulnerability, stressful life events, medications, and medical problems. Its believed that several of these forces interact to bring on depression.
To be sure, chemicals are involved in this process, but it is not a simple matter of one chemical being too low and another too high. Rather, many chemicals are involved, working both inside and outside nerve cells. There are millions, even billions, of chemical reactions that make up the dynamic system that is responsible for your mood, perceptions, and how you experience life."