General Discussion
In reply to the discussion: More on Cannabis cures cancer..... [View all]cali
(114,904 posts)but I believe that with one exception, all the studies that have been done with hemp oil for cancer, have either been conducted on mice or rats or on cancerous cell material. Guzman conducted a study with 9 people with advanced glioblastoma that entailed administration of a THC formula, through tubes, directly to the tumor site. All the patients died within a year. There was no control group in this study so it's impossible to state that the protocol did or did not prolong their lives. Clearly it did not cure the cancer.
Here's the abstract. You can read more at the link:
Tetrahydrocannabinol (THC) and other cannabinoids inhibit tumour growth and angiogenesis in animal models, so their potential application as antitumoral drugs has been suggested. However, the antitumoral effect of cannabinoids has never been tested in humans. Here we report the first clinical study aimed at assessing cannabinoid antitumoral action, specifically a pilot phase I trial in which nine patients with recurrent glioblastoma multiforme were administered THC intratumoraly. The patients had previously failed standard therapy (surgery and radiotherapy) and had clear evidence of tumour progression. The primary end point of the study was to determine the safety of intracranial THC administration. We also evaluated THC action on the length of survival and various tumour-cell parameters. A dose escalation regimen for THC administration was assessed. Cannabinoid delivery was safe and could be achieved without overt psychoactive effects. Median survival of the cohort from the beginning of cannabinoid administration was 24 weeks (95% confidence interval: 1533). Δ9-Tetrahydrocannabinol inhibited tumour-cell proliferation in vitro and decreased tumour-cell Ki67 immunostaining when administered to two patients. The fair safety profile of THC, together with its possible antiproliferative action on tumour cells reported here and in other studies, may set the basis for future trials aimed at evaluating the potential antitumoral activity of cannabinoids.
http://www.nature.com/bjc/journal/v95/n2/full/6603236a.html
I want to add, that the article in the op isn't a scientific one. It's a piece that pushes the use of hemp oil and the author's book- that's fine, but that's what it is and it doesn't address Guzman's study. Hell, the guy even claims that it was a hemp oil study, but that's not the case with any of Guzman's work.
Far more research needs to be conducted. It's funny, how here on DU we scoff at wingnuts who eschew science but quite often there are those who here who do the same. My point in this thread is that there is no evidence at all that hemp oil or THC or any of the other properties of cannabis, cure cancer. There's a slight body of encouraging research, and there are anecdotal accounts often in the form of testimonials. The latter is not, of course, falsifiable.