General Discussion
In reply to the discussion: Meditation 'works just as well as anti-depressants' [View all]pnwmom
(110,263 posts)the effectiveness of SSRI's and other depression meds for the most serious forms of depression, not the milder cases.
IOW, doctors are giving SSRI's to patients without full-blown depression even though the research fails to show a benefit for this group.
http://www.newscientist.com/article/dn13375-prozac-does-not-work-in-majority-of-depressed-patients.html#.Usu2QhbvxTQ
The antidepressant Prozac and related drugs are no better than placebo in treating all but the most severely depressed patients, according to a damaging assessment of the latest generation of antidepressants.
SSRIs, or selective serotonin reuptake inhibitors, were supposed to revolutionise care of depression - by treating symptoms without the side effects of older drugs, such as tricyclics.
But despite selling in vast quantities, a new meta-analysis of these drugs, from data presented to the US Food and Drug Administration (FDA), appears to suggest that for most patients they do not work. A previous study had indicated that the benefits of antidepressants might be exaggerated.
SNIP
They did detect some benefits in the most severely depressed patients. But conclude that in this group the small effect is "due to decreased responsiveness to placebo, rather than increased responsiveness to medication".