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RainDog

(28,784 posts)
17. Good information
Fri Apr 25, 2014, 05:13 PM
Apr 2014

thanks for posting.

one problem, as mentioned, was the correlation with tobacco use, of course.

I wonder how this work compares to reports of lower levels of fasting insulin, cholesterol and weight. Caloric intake versus bmi, etc.

http://www.sciencedaily.com/releases/2013/05/130515085208.htm



http://www.amjmed.com/article/S0002-9343%2813%2900200-3/abstract

There are limited data regarding the relationship between cannabinoids and metabolic processes. Epidemiologic studies have found lower prevalence rates of obesity and diabetes mellitus in marijuana users compared with people who have never used marijuana, suggesting a relationship between cannabinoids and peripheral metabolic processes. To date, no study has investigated the relationship between marijuana use and fasting insulin, glucose, and insulin resistance.

Methods
We included 4657 adult men and women from the National Health and Nutrition Examination Survey from 2005 to 2010. Marijuana use was assessed by self-report in a private room. Fasting insulin and glucose were measured via blood samples after a 9-hour fast, and homeostasis model assessment of insulin resistance (HOMA-IR) was calculated to evaluate insulin resistance. Associations were estimated using multiple linear regression, accounting for survey design and adjusting for potential confounders.

Results
Of the participants in our study sample, 579 were current marijuana users and 1975 were past users. In multivariable adjusted models, current marijuana use was associated with 16% lower fasting insulin levels (95% confidence interval [CI], −26, −6) and 17% lower HOMA-IR (95% CI, −27, −6). We found significant associations between marijuana use and smaller waist circumferences. Among current users, we found no significant dose-response.

Conclusions
We found that marijuana use was associated with lower levels of fasting insulin and HOMA-IR, and smaller waist circumference.


Studies also indicate THC provides cardio protection in low doses -

A single ultra low dose of THC before ischemia is a safe and effective treatment that reduces myocardial ischemic damage.

http://www.ncbi.nlm.nih.gov/pubmed/23537701

(the same scientist demonstrated neuro-protection from low dose THC as well)
http://link.springer.com/article/10.1007/s00221-012-3186-5


Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production.

http://www.ncbi.nlm.nih.gov/pubmed/16444588

THC fights hardened arteries.

The study is behind a pay wall, but here's one article about it, below the study link.

http://www.nature.com/nature/journal/v434/n7034/full/434708a.html

http://www.webmd.com/heart-disease/news/20050406/marijuana-chemical-fights-hardened-arteries

The active ingredient in marijuana that produces changes in brain messages appears to fight atherosclerosis -- a hardening of the arteries.

The results may be due to THC's anti-inflammatory properties, write the researchers, who included François Mach, MD, of the cardiology division at University Hospital in Geneva, Switzerland. Inflammation has been shown to be associated with the development of atherosclerosis.


This, of course, does not mean that some people can't have increased heart rates from the use of marijuana - but does demonstrate some cardio-protective features in low doses - lower than those most people would have if they inhaled marijuana.

Recommendations

0 members have recommended this reply (displayed in chronological order):

Thank you for your concern trolling 4now Apr 2014 #1
Here's what NORML has to say about that: Comrade Grumpy Apr 2014 #2
Of course this will be ignored, the narrative must stand. nt. Rex Apr 2014 #14
"There is a strong association with schizophrenia. That much is proven." antiquie Apr 2014 #3
Association is NOT causation Yo_Mama Apr 2014 #20
Yes. That's what meta analysis has shown RainDog Apr 2014 #23
Right - for some people it may be causative, we don't know how to distinguish that Yo_Mama Apr 2014 #24
But the meta analyses ruled out causation RainDog Apr 2014 #26
They didn't rule out causation in indivduals Yo_Mama Apr 2014 #28
If individuals were at risk for schizo-affective disorders RainDog Apr 2014 #30
It's interesting that someone was writing about this RainDog Apr 2014 #29
Chances are, these "case studies" were couch-potatoes long before smoking weed... Cooley Hurd Apr 2014 #4
These studies are ridiculous... First of all, what kind of weed was it? SomethingFishy Apr 2014 #11
and my munchies were always for fresh whole foods like fruits & veggies eShirl Apr 2014 #12
My point is that a specialized reporting system is being suggested Yo_Mama Apr 2014 #25
taurine metabolic byproduct. hobbit709 Apr 2014 #5
Thank gawd we have prohibition to save these young people. n/t theaocp Apr 2014 #6
Here some FUD, there some FUD, everywhere some FUD FUD! Rex Apr 2014 #7
Thank you for posting this…this sounds important for anyone who wants to start young and.. Tikki Apr 2014 #8
because your physician will have as much data as went into and came out of this study: zero. Warren Stupidity Apr 2014 #15
Or he will have info… Tikki Apr 2014 #16
Or if you have early symptoms. Yo_Mama Apr 2014 #19
Yes, we need to tell our physicians everything we regularly put into our systems. Tikki Apr 2014 #22
Which it will not necessarily be if a mandatory reporting system is instituted. Yo_Mama Apr 2014 #27
This message was self-deleted by its author antiquie Apr 2014 #9
I've been smoking pot for over 30 years Politicalboi Apr 2014 #10
Exactly - some people can't eat wheat - Yo_Mama Apr 2014 #18
6 Sodas? otohara Apr 2014 #37
Thanks for posting. Union Scribe Apr 2014 #13
Good information RainDog Apr 2014 #17
paranoia, with munchies? Who knew? 2pooped2pop Apr 2014 #21
Now that pot will soon be legal everywhere the fear mongering Lint Head Apr 2014 #31
In people prone to vasoconstriction, pot has caused amputations. Yo_Mama Apr 2014 #32
For people with ulcers aspirin can cause them to bleed and death. Lint Head Apr 2014 #34
And the tobacco had absolutely no effect? Give me a break. hobbit709 Apr 2014 #36
All those reported were cigarette smokers, too RainDog Apr 2014 #38
"higher caloric intake"... Jesus Malverde Apr 2014 #33
I think the suggestion that marijuana is somehow a miracle drug that never brings harm and cures hedgehog Apr 2014 #35
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