Tell Young People the Truth: E-Cigarettes and Vaping Flavors Help People Quit Smoking (Alternet)

[pnwmom]

95. Let the producers submit their research to the FDA for its review.

Till then, we have the research of independent researchers like those at UCal Riverside and the Fred Hutchinson Cancer Research Center, who have found toxins in the vapor of the ecigs they've tested.

And your assumption that no "flavor" can be toxic is incorrect. More than one have been shown to be. For example:

http://www.sciencedirect.com/science/article/pii/S0887233313002610

Highlights
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Most cinnamon-flavored refill fluids were cytotoxic to embryonic and adult cells.
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Human embryonic stem cells were more sensitive than adult pulmonary fibroblasts.
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Four chemicals were identified in cinnamon-flavored refill fluids.
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Dipropylene glycol and vanillin had low cytotoxicity.
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Cinnamaldehyde and 2-methoxycinnamaldehyde were cytotoxic in the MTT assay.
Abstract
In a prior study on electronic cigarette (EC) refill fluids, Cinnamon Ceylon was the most cytotoxic of 36 products tested. The purpose of the current study was to determine if high cytotoxicity is a general feature of cinnamon-flavored EC refill fluids and to identify the toxicant(s) in Cinnamon Ceylon. Eight cinnamon-flavored refill fluids, which were screened using the MTT assay, varied in their cytotoxicity with most being cytotoxic. Human embryonic stem cells were generally more sensitive than human adult pulmonary fibroblasts. Most products were highly volatile and produced vapors that impaired survival of cells in adjacent wells. Cinnamaldehyde (CAD), 2-methoxycinnamaldehyde (2MOCA), dipropylene glycol, and vanillin were identified in the cinnamon-flavored refill fluids using gas chromatography–mass spectrometry and high-pressure liquid chromatography (HPLC). When authentic standards of each chemical were tested using the MTT assay, only CAD and 2MOCA were highly cytotoxic. The amount of each chemical in the refill fluids was quantified using HPLC, and cytotoxicity correlated with the amount of CAD/product. Duplicate bottles of the same product were similar, but varied in their concentrations of 2MOCA. These data show that the cinnamon flavorings in refill fluids are linked to cytotoxicity, which could adversely affect EC users.

Corresponding author at: Department of Cell Biology and Neuroscience, University of California, Riverside, CA 92521, United States.



Here, a discussion among vapers about what chemical flavorings are not safe to vape: (One of them acknowledges that most companies who make the flavors haven't tested them for safety.)

http://www.reddit.com/r/electronic_cigarette/comments/152zy6/what_chemicals_not_to_vape/