The 2010 Princeton study proved that the HFCS molecules is not the same as, nor is it metabolized like glucose. From the study:
High-fructose corn syrup and sucrose are both compounds that contain the simple sugars fructose and glucose, but there at least two clear differences between them. First, sucrose is composed of equal amounts of the two simple sugars -- it is 50 percent fructose and 50 percent glucose -- but the typical high-fructose corn syrup used in this study features a slightly imbalanced ratio, containing 55 percent fructose and 42 percent glucose. Larger sugar molecules called higher saccharides make up the remaining 3 percent of the sweetener.
Glucose (found in cane/beet sugar) with its different molecular design requires the expenditure of more energy for our bodies to be able to use it, thereby using more energy to store and fewer calories left over as fat as a result. Lacking the need for the additional step, HFCS and its large saccharides molecules, go directly to storage in the brown fat of the body. This is not good.
Likewise, further studies on
GMO rice in 2011 shows that the genetically-altered RNA of the rice was found intact after oral ingestion within the liver and other organs of mice. The cells there:
...were found to bind to the low-density lipoprotein receptor adapter protein 1 (LDLRAP1) mRNA, which inhibited LDLRAP1 expression in liver, and consequently decreased LDL (cholesterol) removal.
LDL cholesterol accumulations in the arteries of the heart can cause heart attacks and death. So this means that GMOs can directly impact cellular metabolism and thereby result in mutation or other dire consequences for bodily functions.

- If the same is true of all GMOs as has been found in the GMO rice, then it would explain much of why immune diseases and cancers are so prevalent in the human species.