Dieting results in long term changes to hormones and muscle fibers.

[eridani]

276. Type II diabetes is not "divorced from" obesity. The same genes cause both diabetes and obesity

Last edited Sun May 6, 2012, 06:59 PM - Edit history (1)

That does not logically qualify as "divorce." The apparent increase in Type II is because of the LOWERING OF THE AGE OF ONSET of diabetic symptoms, which is definitely caused mostly by environmental factors. You are genetically diabetic whether symptoms ever develop or not.

And the article did not say that fat prevents the catabolism of muscle. The fact that it inhibits the catabolism of muscle does not change the fact that the energy input required to catabolise protein is lower than that required to catabolise fat. You get more energy out of fat, but you need more energy input initially for that to happen.

And if fat causes diabetic symptoms, why is it that physical removal of fat produces no change in blood chemistry whatsoever?

http://content.nejm.org/cgi/content/abstract/350/25/2549

Liposuction decreased the volume of subcutaneous abdominal adipose tissue by 44 percent in the subjects with normal glucose tolerance and 28 percent in those with diabetes; those with normal oral glucose tolerance lost 9.1±3.7 kg of fat (18±3 percent decrease in total fat, P=0.002), and those with type 2 diabetes lost 10.5±3.3 kg of fat (19±2 percent decrease in total fat, P<0.001). Liposuction did not significantly alter the insulin sensitivity of muscle, liver, or adipose tissue (assessed by the stimulation of glucose disposal, the suppression of glucose production, and the suppression of lipolysis, respectively); did not significantly alter plasma concentrations of C-reactive protein, interleukin-6, tumor necrosis factor , and adiponectin; and did not significantly affect other risk factors for coronary heart disease (blood pressure and plasma glucose, insulin, and lipid concentrations) in either group.