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UglyGreed

(7,661 posts)
66. Addicted is
Mon Jun 8, 2015, 09:48 AM
Jun 2015

sometimes associated with weakness and at times criminal activity. Maybe we should use the term Discontinuation syndrome like they do for Antidepressants......

Main article: Antidepressant discontinuation syndrome
Antidepressant discontinuation symptoms were first reported with imipramine, the first tricyclic antidepressant (TCA), in the late 1950s, and each new class of antidepressants has brought reports of similar conditions, including monoamine oxidase inhibitors (MAOIs), SSRIs, and SNRIs. As of 2001, at least 21 different antidepressants, covering all the major classes, were known to cause discontinuation syndromes.[125] The problem has been poorly studied, and most of the literature has been case reports or small clinical studies; incidence is hard to determine and controversial.[125]

People with discontinuation syndrome have been on an antidepressant for at least four weeks and have recently stopped taking the medication, either abruptly or after a fast taper.[126] Common symptoms include flu-like symptoms (nausea, vomiting, diarrhea, headaches, sweating), sleep disturbances (insomnia, nightmares, constant sleepiness), sensory/movement disturbances (imbalance, tremors, vertigo, dizziness, electric-shock-like experiences), mood disturbances (dysphoria, anxiety, agitation) and cognitive disturbances (confusion and hyperarousal).[126][127][128] Over fifty symptoms have been reported.[129]

Most cases of discontinuation syndrome last between one and four weeks, are relatively mild, and resolve on their own; in rare cases symptoms can be severe or extended.[126] Paroxetine and venlafaxine seem to be particularly difficult to discontinue and prolonged withdrawal syndrome lasting over 18 months have been reported with paroxetine.[125][130][131]

With the explosion of use and interest in SSRIs in the late 1980s and early 1990s, focused especially on Prozac, interest grew as well in discontinuation syndromes.[132] In the late 1990s, some investigators thought that symptoms that emerged when antidepressants were discontinued, might mean that antidepressants were causing addiction, and some used the term "withdrawal syndrome" to describe the symptoms. Addictive substances cause physiological dependence, so that drug withdrawal causes suffering. These theories were abandoned, since addiction leads to drug-seeking behavior, and people taking antidepressants do not exhibit drug-seeking behavior. The term "withdrawal syndrome" is no longer used with respect to antidepressants, to avoid confusion with problems that arise from addiction.[126][133][134] There are case reports of antidepressants being abused, but these are rare and are mostly limited to antidepressants with stimulant effects and to people who already had a substance abuse disorder.[135] A 2012 comparison of the effects of stopping therapy with benzodiazepines and SSRIs argued that because the symptoms are similar, it makes no sense to say that benzodiazepines are addictive while SSRIs are not.[136] Responses to that review noted that there is no evidence that people who stop taking SSRIs exhibit drug-seeking behavior while people who stop taking benzodiazepines do, and that the drug classes should be considered differently.[137][138]

http://en.wikipedia.org/wiki/Antidepressant

Just sayin"

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0 members have recommended this reply (displayed in chronological order):

Yes, I felt the same effect with prednisone. Just plain grouchy and irritable. SharonAnn Jun 2015 #1
I thank you for that discription. My severely disabled daughter took prednisone for years to try to jwirr Jun 2015 #27
It depends on the drug. Millions are on anti hypertensive medications still_one Jun 2015 #2
Thanx - I recovered with some leftover lung damage. My concern is obviously for NYC_SKP blm Jun 2015 #4
Did you notice his posts after Sandy Hook? After Charlie Hebdo? KittyWampus Jun 2015 #35
no….actually, I am unaware there was a problem there…. blm Jun 2015 #39
I was on prednisone for two weeks bigwillq Jun 2015 #3
I was on steroids for a few weeks and it completely changed me. bravenak Jun 2015 #5
Imagine 2 months or 2years. I can't imagine past the 4 months I dealt with it. blm Jun 2015 #7
That must have been a trying time. bravenak Jun 2015 #9
I feel positive that is the issue with the most recently banned member. blm Jun 2015 #10
I think so too. bravenak Jun 2015 #11
I have been on prednisone on and off BronxBoy Jun 2015 #14
That is classic 'Pred-Head' blm Jun 2015 #18
or it's other name Horse with no Name Jun 2015 #58
lolol blm Jun 2015 #61
not weed, been on that medication for 20+ years... snooper2 Jun 2015 #6
heheh…and THAT is why it should be legal…..everywhere. blm Jun 2015 #8
Back in the day we called that being a Dead Head. bluesbassman Jun 2015 #29
and still do….. blm Jun 2015 #31
already addressed Romeo.lima333 Jun 2015 #12
can you expound on that? blm Jun 2015 #21
sorry for being cryptic my op said that i think that maybe nyc_skip was going thru the same pain Romeo.lima333 Jun 2015 #22
I haven't seen other OPs about this. blm Jun 2015 #23
no they were posts inside your post. i didnt read the replies before i posted. so i wrote what i Romeo.lima333 Jun 2015 #24
how awful for you! shanti Jun 2015 #13
It happens to MOST everyone who uses it. blm Jun 2015 #16
Corticosteroids act like hormones. NutmegYankee Jun 2015 #38
So sorry you had to endure this, blm MissDeeds Jun 2015 #15
Live and learn, then help others. blm Jun 2015 #25
Hell, if I drink a Red Bull it changes my personality! Have no idea why. Rex Jun 2015 #17
Nyquil gives me all those fun side effects on the bottle Scootaloo Jun 2015 #26
Wow - so far it never hit me like that. blm Jun 2015 #33
I totally agree with what you're saying. I've made a few remarks on DU that I wish I had not said. BlueJazz Jun 2015 #19
After 14 years here many have become family, even though I don't do blm Jun 2015 #20
I nearly moved into a hotel after two days of Ilsa Jun 2015 #28
I've been on various doses Nite Owl Jun 2015 #30
Exactly. Works great…..BUT……... blm Jun 2015 #32
Thank you so much for posting this. I feel awful for NYC_SKP. scarletwoman Jun 2015 #34
I've struggled with my health issues that pale in comparison to his, blm Jun 2015 #52
Sometimes a troll is just a troll. Interesting to see an over the internet diagnoses KittyWampus Jun 2015 #36
Kitty, I am submitting firsthand experience, as are others, and blm Jun 2015 #40
Pain and lack of proper UglyGreed Jun 2015 #37
Oh - did I forget to mention the Oxycodone? blm Jun 2015 #41
Was NYC taking UglyGreed Jun 2015 #43
He probably was - I cut back a lot myself so my body wouldn't become blm Jun 2015 #44
I like to use the UglyGreed Jun 2015 #45
heheh…..dependent sounds so………..dependent. blm Jun 2015 #50
Addicted is UglyGreed Jun 2015 #66
Sounds WAY better. blm Jun 2015 #67
so many people have crashed and burned here olddots Jun 2015 #42
I had the opposite effect when I was on Pred. Jamastiene Jun 2015 #46
That's the first I heard of that, but then, I was on other stuff for pain. blm Jun 2015 #47
I have De Quervain Syndrome in Jamastiene Jun 2015 #48
Funny how different human beings can be. Cortisone shots never worked on me - blm Jun 2015 #49
I hope you can get relief too. Jamastiene Jun 2015 #53
I've taken prednisone for many years off and on Horse with no Name Jun 2015 #59
Yes, I have personal experience with this. kcr Jun 2015 #51
After two head injuries...car accidents (not my fault)...I lost my ability to sleep. Everything libdem4life Jun 2015 #54
wishing you the best….we're here to listen if you need understanding audience. blm Jun 2015 #55
Thank you. Which forum? libdem4life Jun 2015 #56
Go to Health Forum - there are a number of sub-forums. blm Jun 2015 #62
Thanks. libdem4life Jun 2015 #63
Agreed. I have had some pretty signficant health issues over the last few years Horse with no Name Jun 2015 #57
Thank you for posting this. I've thought there was more to the story blm Jun 2015 #60
Prednisone: the greatest drug that ever gave you a buttload of side-effects Nac Mac Feegle Jun 2015 #64
there are a couple of things you can do Horse with no Name Jun 2015 #65
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