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Dengue vaccine proves 100% effective in human trials [View all]
http://www.wired.co.uk/news/archive/2016-03/17/dengue-vaccine-human-trial-complete-protectionAn experimental vaccine against the dengue virus has been found to protect 100 percent of recipients in a clinical trial carried out by the USA's National Institute of Allergy and Infectious Diseases (NIAID).
In the NIAID trial 21 people were vaccinated with TV003, while 20 received a placebo. Six months later they returned to be infected with a mild version of dengue-2. All 21 people who'd received the vaccine were protected against infection. All 20 members of the placebo group contracted dengue. A modified version of the vaccine is now being developed in an attempt to treat the related Zika virus.
TV003 is a live attenuated vaccine, meaning that, like measles, mumps, and flu vaccines, it's made by creating a greatly weakened version of the virus it's designed to combat. Specifically, this vaccine involves a combination of four recombinant dengue vaccine candidate viruses, designed to combat all four major dengue virus serotypes.
The volunteers who received the vaccine experienced no ill effects from it and developed only a mild rash, which they didn't notice and which vanished entirely in five to ten days. All subjects successfully developed antibodies against dengue.
In the NIAID trial 21 people were vaccinated with TV003, while 20 received a placebo. Six months later they returned to be infected with a mild version of dengue-2. All 21 people who'd received the vaccine were protected against infection. All 20 members of the placebo group contracted dengue. A modified version of the vaccine is now being developed in an attempt to treat the related Zika virus.
TV003 is a live attenuated vaccine, meaning that, like measles, mumps, and flu vaccines, it's made by creating a greatly weakened version of the virus it's designed to combat. Specifically, this vaccine involves a combination of four recombinant dengue vaccine candidate viruses, designed to combat all four major dengue virus serotypes.
The volunteers who received the vaccine experienced no ill effects from it and developed only a mild rash, which they didn't notice and which vanished entirely in five to ten days. All subjects successfully developed antibodies against dengue.
Fuck yeah science
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