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IronLionZion

(50,842 posts)
Fri Jun 2, 2017, 08:58 AM Jun 2017

One short letter's huge impact on the opioid epidemic [View all]

(CNN)Every day, 91 Americans die from an opioid overdose. Drug overdoses overall -- most of them from opioid painkillers and heroin -- are the leading cause of accidental death in the US, killing more people than guns or car accidents. In fact, while Americans represent only about 5% of the global population, they consume about 80% of the world's opioid painkillers. But how did we get to this point?

Many public health experts point to a simple five-sentence letter to the editor published in a 1980 edition of the New England Journal of Medicine. The 101-word letter, titled "Addiction Rare in Patients Treated with Narcotics," was signed by Jane Porter and Dr. Hershel Jick of Boston University, who said that of their 11,000-plus patients treated with narcotics, there were only four cases of addiction.

And although this letter provided no further evidence and was not a peer-reviewed study, it has often been cited as proof of the safety of prescribing long-term narcotics for chronic pain.

This week, the journal published yet another letter to the editor, this one an analysis from researchers at the Institute for Clinical Evaluative Sciences of how frequently Porter and Jick's letter has been cited by other researchers and physicians in studies and journals since its publication. The analysis found 608 citations of the initial letter as of May 30, 72% of them pointing to it as proof that addiction was rare among long-term narcotic users.

Dr. David Juurlink, one of the researchers involved in the analysis, wrote in an email that the "5-sentence letter to the editor in medicine's most prestigious journal was leveraged as proof that opioids could be used safely over the long term, even though it offered no evidence to support that claim. It's clear that many of the authors who cited it hadn't actually read it."

http://www.cnn.com/2017/06/01/health/opioid-epidemic-1980-letter-origins-study/index.html

Some assholes need alternative facts to sell drugs. Hook em while they're young and find new ones to replace the dead.

Ohio is suing 5 drug companies. Kentucky and other states have done so in recent years. Rush Limbaugh and other prominent conservative blowhards have been high on drugs. Someone should test our president.

No matter how many small rural towns across red states have heroin addictions and overdoses and people catching HIV from sharing dirty needles in rural parts of Indiana while Mike Pence was governor, too many still believe it is an "urban" problem.

Trump country is heavily medicated.

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Where do legit severe chronic pain patients fit in? Kittycow Jun 2017 #1
The recommended dosages were known to be too high IronLionZion Jun 2017 #3
Well in my case. .. Kittycow Jun 2017 #4
You're right about the database JesterCS Jun 2017 #5
Is it national? Does it track if you go out of state? IronLionZion Jun 2017 #10
Not national Chuuku Davis Jun 2017 #25
Ya not national. State by state JesterCS Jun 2017 #35
Sorry to hear that IronLionZion Jun 2017 #6
I would have to agree with coming down hard on bad doctors. Kittycow Jun 2017 #7
This message was self-deleted by its author Warren DeMontague Jun 2017 #23
Yep. Addiction is a medical problem and ought to be treated as such. hunter Jun 2017 #32
This message was self-deleted by its author Warren DeMontague Jun 2017 #33
We've accepted that some percentage of the population are alcoholics. Mariana Jun 2017 #39
Oh bullshit. "Chronic severe pain" can be seen on an MRI when a patient has bone cancer or spinal anneboleyn Jun 2017 #13
This message was self-deleted by its author Warren DeMontague Jun 2017 #24
Why the opioid addiction and abuse problem? IronLionZion Jun 2017 #27
I'll say that I would rather have the meds and not need them thecrow Jun 2017 #34
Abusers ruin it for everyone IronLionZion Jun 2017 #36
Abusers don't ruin it for anyone. Mariana Jun 2017 #40
We've passed and repealed prohibition in this country IronLionZion Jun 2017 #49
I can't stand the anti-opioid hysteria as we have seen the suffering of REAL patients in our own anneboleyn Jun 2017 #11
+1000. Crunchy Frog Jun 2017 #14
Right. Fucking. ON, anneboleyn. Your fury and frustration towards every aspect of this Leghorn21 Jun 2017 #18
I sense your frustration IronLionZion Jun 2017 #29
Except that it DOES stop them from getting their meds. Coventina Jun 2017 #47
This message was self-deleted by its author Warren DeMontague Jun 2017 #20
Don't forget meditation! Oh! And also "counseling" to make you accept pain will be your life. Coventina Jun 2017 #44
Kick. dalton99a Jun 2017 #2
One letter. A convenient scapegoat that lets us ignore lots of other impacts. kcr Jun 2017 #8
Drug companies are exploiting people IronLionZion Jun 2017 #9
This isn't tobacco. Real people, with real diseases, are suffering hideously, and if these drugs anneboleyn Jun 2017 #12
Agree with you about indifference to pain patients. Kittycow Jun 2017 #15
Pharmaceutical companies are being sued? It must be Tuesday. kcr Jun 2017 #17
This message was self-deleted by its author Warren DeMontague Jun 2017 #21
It's Friday and who's ramping up the drug war? IronLionZion Jun 2017 #30
Sorry. I thought that was old enough for DU. Apparently not. kcr Jun 2017 #48
The medical version of the 1975 "Global Cooling" article in Newsweek hatrack Jun 2017 #16
That's exactly what it is. kcr Jun 2017 #19
I'm sure if we make it harder for people in crippling pain to get relief, good things will happen Warren DeMontague Jun 2017 #22
I want to do something about drug overdoses and deaths IronLionZion Jun 2017 #28
This message was self-deleted by its author Warren DeMontague Jun 2017 #31
The problem isn't oipiates given for chronic pain Warpy Jun 2017 #26
Thanks for sharing that IronLionZion Jun 2017 #38
They might not have been addicts. They might have been dependent Warpy Jun 2017 #42
Would you explain the difference between addiction and dependency, please? Mariana Jun 2017 #43
I answered someone else about that last night Warpy Jun 2017 #45
Dependency means you need the drug to live a decent life. Coventina Jun 2017 #46
I don't know the answer to this. I used oxycontin for weeks when I broke my shoulder 5 or so years seaglass Jun 2017 #37
Very soon a simple genetic test will identify people highly likely to be an addict. AngryAmish Jun 2017 #41
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