Down syndrome reversed in newborn mice with single injection

[d_r]

13. Down syndrome

is caused by an extra copy of chromosome 21.
Down Syndrome is associated with many physiological traits, including a smaller than average size cerebellum.
In this case, mice were genetically engineered to have additional chromosomal material analogous to Down Syndrome in humans.
At birth, the mice were injected with an agonist that is thought to promote brain development.
The mice that were injected at birth subsequently showed improved development in cerebellum size.
Even if this works for humans, this does not mean that this would necessarily change brain size or functioning in older children or adults.