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another_liberal

(8,821 posts)
Sat Dec 21, 2013, 10:11 PM Dec 2013

Anti-ageing compound set for human trials after turning clock back for mice. [View all]

Source: The Guardian

Australian and US researchers hope an anti-ageing compound could be trialled on humans as early as next year, following a key breakthrough that saw the ageing process reversed in mice. The study, involving Harvard University and the University of NSW, discovered a way of restoring the efficiency of cells, completely reversing the ageing process in muscles. Two-year-old mice were given a compound over a week, moving back the key indicators of ageing to that of a six-month-old mouse. Researchers said this was the equivalent of making a 60-year-old person feel like a 20-year-old.

It’s hoped the research, published in Cell, will be expanded to humans as early as next year, with scientists set to look at how the theory of age reversal can be used to treat diseases such as cancer, dementia and diabetes.

The research focused on an area of cells, called mitochondria, which produce energy. Over time, the communication between this area and the cell nucleus degrades, leading to the ageing process. Researchers injected a chemical called nicotinamide adenine dinucleotide, or NAD, which reduces in the body as we age. The addition of this compound led to the radical reversal in the ageing of the mice.

(snip)

Read more: http://www.theguardian.com/science/2013/dec/20/anti-ageing-human-trials



If this pans out, Social Security checks will soon be going to retirees who are, physically at least, only twenty-five!
78 replies = new reply since forum marked as read
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I'll volunteer, cause I'm not liking this getting old thing at all. notadmblnd Dec 2013 #1
TELL me about it. I weigh the same, but my clothes dont fit anymore. Odd.... 7962 Dec 2013 #23
it's not so much my looks, although I don't like the grey hair and wrinkles notadmblnd Dec 2013 #44
i REFUSE to have Andy Rooney eyebrows! 7962 Dec 2013 #47
Yeah, my eyesight is gone. I just found out that I have cataracts. RebelOne Jan 2014 #75
I absolutely LOVE getting old! Kablooie Dec 2013 #26
You and me both theHandpuppet Dec 2013 #35
I will volunteer, because I hate this getting old thing. RebelOne Jan 2014 #74
The biology of the mouse genome does not always correspond to the human lostincalifornia Dec 2013 #2
The researchers seem to think there is promise in human trials. another_liberal Dec 2013 #4
I hope so lostincalifornia Dec 2013 #6
Just what the world needs Scootaloo Dec 2013 #3
Where do I volunteer? Curmudgeoness Dec 2013 #5
It's a known fact... RoccoR5955 Dec 2013 #7
We don't know if it would extend life significantly. Curmudgeoness Dec 2013 #8
I could take the same number of years Diego_Native 2012 Dec 2013 #59
Yes I'll take feeling better.... abakan Dec 2013 #61
Welcome to DU, abakan. Curmudgeoness Dec 2013 #62
Thanks for the welcome.. abakan Dec 2013 #67
Welcome to the DU abakan chknltl Dec 2013 #68
You may be right... abakan Jan 2014 #72
Right,...just picture Dorian Grey. Spitfire of ATJ Dec 2013 #10
No fair. Curmudgeoness Dec 2013 #17
I like to think I'm gonna LOOK like I had fun. Spitfire of ATJ Dec 2013 #21
LOL Curmudgeoness Dec 2013 #22
Just a tip, Curmudgeoness...I've seen significant Surya Gayatri Dec 2013 #32
Add some black pepper Richard D Dec 2013 #37
Who knew? Thanks, Richard D... Surya Gayatri Dec 2013 #41
That is a lot of tumeric. Curmudgeoness Dec 2013 #48
Tumeric is the basic, bright yellow spice in Indian curies and has Surya Gayatri Dec 2013 #55
Thanks. I know all about being my own guinea pig. Curmudgeoness Dec 2013 #57
Like the old white racists will never go meet their black maker. loudsue Dec 2013 #58
yea.....getting old is not for sissies. Maraya1969 Dec 2013 #14
Dude! You read my mind. skamaria Dec 2013 #70
I volunteer! femmocrat Dec 2013 #9
When that happens shanti Dec 2013 #18
My first thought as well Cirque du So-What Dec 2013 #66
Back off!! I go first!* darkangel218 Dec 2013 #54
Oh great, now the koch brothers will be around forever. diane in sf Dec 2013 #11
Not necessarily . . . another_liberal Dec 2013 #12
and one cannot repair a broken soul... or one which has expired on the vine tomm2thumbs Dec 2013 #56
I think you can already get this stuff at a health food store. Maraya1969 Dec 2013 #13
I am getting some T O M O R R O W!! YOHABLO Dec 2013 #15
i just bought some on ebay shanti Dec 2013 #50
If it sounds too good to be true, Curmudgeoness Dec 2013 #19
Isn't this vit B3? Tumbulu Dec 2013 #16
Good question. another_liberal Dec 2013 #27
It's happening. JaneyVee Dec 2013 #20
Is this akin to NADP+ bucolic_frolic Dec 2013 #24
Ponce de Leon Must Feel Vindicated DallasNE Dec 2013 #25
Dick Cheney is already demanding access to the treatments, or I miss my guess. another_liberal Dec 2013 #28
And then they will raise the retirement age to 500. Live and Learn Dec 2013 #29
I could deal with that - I'd like to feel young forever kysrsoze Dec 2013 #31
Not I. It's not like this would stop all the other BS life throws at you. Live and Learn Dec 2013 #33
Of you could look at it this way theHandpuppet Dec 2013 #36
Not to mention PasadenaTrudy Dec 2013 #42
I'll believe it when I see the results passiveporcupine Dec 2013 #30
Really. SheilaT Dec 2013 #34
Many treatements you take for granted were tested on mice first, can you name Bluenorthwest Dec 2013 #38
And of course, mice, being pan-dimensional beings elias7 Dec 2013 #43
The anti-science, pro-death sentiment in some of these replies... politichew Dec 2013 #39
Agreed. DavidDvorkin Dec 2013 #46
I'm not anti-science PasadenaTrudy Dec 2013 #49
+1. My mom's well into her 80s and so many of her friends are gone, even younger ones winter is coming Dec 2013 #63
I remember reading the following article a couple of years ago. Live and Learn Dec 2013 #51
I just watched the second Star Trek movie on DVD Thor_MN Dec 2013 #40
From the article drm604 Dec 2013 #45
I take it their regular science writer ... GeorgeGist Dec 2013 #52
I dont mind saying that i would absolutely love to live forever. darkangel218 Dec 2013 #53
Absolutely. Me too. DavidDvorkin Dec 2013 #60
Amen to that. There are just too many things of which I'd like to see the outcome. n/t ChisolmTrailDem Jan 2014 #76
Great! rrneck Dec 2013 #64
Being young once Riftaxe Dec 2013 #65
What afflictions? Curmudgeoness Dec 2013 #71
Wasteful science loyalsister Dec 2013 #69
Benjamin Button! tblue Jan 2014 #73
I'll believe that when I see it Warpy Jan 2014 #77
Like that thought... civillawyer Jan 2014 #78
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