I follow lots of national and local news orgs (and some international ones) as well as individual reporters.
I get news information as it is happening usually long before I hear it from anywhere else.
On the fun side I like shows like Supernatural and follow the actors, writers, etc (I have 18 people I follow associated with it). They live tweet during the shows giving a lot if interesting information on it. I get a lot of insight off an on through the day from them. I also follow a guy who draws the Batman comics and see his pencil work on new issues before they are inked. Star wars - a lot of things on that from a group that cosplays for hospitals to a slew of interesting information and podcasts.
I normally just have the one window open for it and about every minute something interesting comes across it.
I also have a list of some well known republicans and conservatives - always fun to see their crap. Especially when they end up wrong on things and have to backpedal (plus I can reply to their crap).
All of that without even using hashtags. Then it gets fun. #Syria is still providing a lot of information from people all over the world for example. A great way to just keep up on a topic. #breaking is usually pretty good for breaking news (but some trollish things here and there).
Not to mention all the giveaways and contests from some places I follow - like book publishers. I just won a free hardcover book, one ebook, virtual meet and greets with authors, and all sorts of cool things.
All this in one place, just kick back and wait for information