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Divernan

(15,480 posts)
45. For ebola, possible but not likely; HIV is a different story.
Tue Jul 29, 2014, 02:08 PM
Jul 2014

If you google Ebola, mutate and airborne, you'll get a lot of links, some of them pure speculation, others more science-based. Since HIV is a retrovirus, it mutates more frequently than ebola.
Based on my ONE course from a very good microbiologist, I think it's unlikely but possible. I'm no scientist - just a layman trying to understand the situation for this and other deadly diseases.

Here's one piece I found well-written:
http://www.skyalgae.info/Home/how-do-virusese-mutate-and-become-airborne
(excerpt)

In general, most viruses don't mutate that often. Notable exceptions are the Human Immunodeficiency Virus (HIV) and the Influenza Virus (Flu). HIV is a retrovirus (it has a "reverse transcriptase" enzyme that enables it to convert its RNA into a complimentary DNA that can "integrate" into the host genes. This is often a situation that results in frequent mutations due to gene sequence "reading errors." The Flu virus also mutates frequently. However, virologists and epidemiologists have found that this RNA virus changes by two mechanisms. One mechanism is by reassorting or recombining. There are many flu viruses and each has a host range specificity. That there are flu viruses that only infect animals of a given species like pigs, ducks and humans. However, passage of a duck flu virus through a pig or vice versa sometimes results in genetic adaptation through reassortment or recombination genes so it becomes infectious in humans. Therefore, monitoring duck and pig flu viruses in addition to human cases are some of the things the CDC does to determine what antigens should be in the next vaccine. In addition to these kinds of big changes in flu virus genes, there are also minor point mutation changes that cause "antigenic drift" so the virus of the same type is slightly different antigenically and can escape elimination by the body's immune response to that type's vaccine.
(It then goes on to discuss airborne)


The ostensibly responsible media are not immune to the temptation to stir these fears. In a May 12 editorial, the New York Times declared: "A modest genetic change might enable Ebola to spread rapidly through the air..."

That very same day, in the news section, Times reporter Lawrence K. Altman, M.D., handled the matter more soberly. Reporting from the Centers for Disease Control and Prevention in Atlanta, he wrote, "The deadly Ebola virus continues to spread in Zaire, chiefly affecting health care workers... [It] apparently spread initially among [doctors] and nurses who operated on a patient in Kikwit." Dr. Altman, an infectious-disease specialist who once worked at the CDC, added, "Transmission presumably was through contaminated blood..."

Can a bloodborne or body fluid-borne virus be transformed by a single mutation into an airborne agent (a "flyer&quot , as the scare scenarios imply? It's conceivable. But it's "probably unlikely," according to virologist Beth Levine, M.D., director of virology research in the infectious diseases division at Columbia University's College of Physicians and Surgeons. "Single amino acid mutations can change the tropism [the residential preference] of a virus" in some experimental situations, Dr. Levine says, "but there haven't been any examples of such mutations actually occurring in nature, changing a virus from a bloodborne or bodily fluid route of transmission to a respiratory route."

So, says Dr. Levine, "The media's claim is not totally without scientific basis. But there are no precedents for it, and it's unlikely.

http://www.columbia.edu/cu/21stC/issue-1.2/Ebola.htm

The WHO and CDC... ReRe Jul 2014 #1
One problelm: locals associate hospitals with dying, so don't take people there. Divernan Jul 2014 #3
Thanks so much for this info! ReRe Jul 2014 #14
Given the precautions Drs. take, I'm concerned it may have gone airborne. Divernan Jul 2014 #16
Airborne... ReRe Jul 2014 #18
I just edited my post to add info re a lot more medical personnel being treated/died Divernan Jul 2014 #19
Oh yes... ReRe Jul 2014 #21
Over 100 medical care providers!?!? Divernan Jul 2014 #23
In that you have to understand that the staff and facilities are not what we are used to here Marrah_G Jul 2014 #29
Will have to try to go listen to... ReRe Jul 2014 #31
100 medical workers of all types, including volunteers. herding cats Jul 2014 #38
They often have crappy equipment and mistakes do happen Marrah_G Jul 2014 #24
I certainly hope you are correct. Divernan Jul 2014 #25
I am in total agreement with that :) Marrah_G Jul 2014 #27
What about the possibility of a new vector, i.e, mosquito? Divernan Jul 2014 #20
That question is way... ReRe Jul 2014 #22
I don't think there is a new vector or that it's airborne Marrah_G Jul 2014 #26
I just found the answer to the... ReRe Jul 2014 #30
I think if Ebola was carried by mosquitoes, hedgehog Jul 2014 #44
Ebola is a virus, and as such hard to adapt to mutiple creatures, as needed with a vector. happyslug Jul 2014 #42
Thank you! ReRe Jul 2014 #46
WHO, CDC and MSF have been working hard at containing this. Marrah_G Jul 2014 #11
I know they have. ReRe Jul 2014 #15
The difficulty in containing it Aerows Jul 2014 #50
Worse problem Aerows Jul 2014 #49
I read a new report... ReRe Jul 2014 #53
Ugly. Aerows Jul 2014 #54
They're quarantining only the sick Warpy Jul 2014 #55
Survival rates vary among the different strains of Ebola. Divernan Jul 2014 #2
I know that there is no vaccine, but do you tblue37 Jul 2014 #5
Excellent questions which need to be thoroughly researched. Divernan Jul 2014 #7
Don't expect Big Pharma to get involved, no profits to be made here Hugabear Jul 2014 #17
Roll Back Malaria program (RBM) pinto Jul 2014 #32
Very interesting and encouraging program Divernan Jul 2014 #34
There are experimental vaccines. herding cats Jul 2014 #40
They *think* this falls within the Zaire Ebola eShirl Jul 2014 #6
In other words, similar but not identical? Divernan Jul 2014 #8
not "similar," but a subset of eShirl Jul 2014 #9
Each strain has variations Marrah_G Jul 2014 #13
And contracting one strain Aerows Jul 2014 #52
It's the Ebola Zaire strain Marrah_G Jul 2014 #12
The CDC on the strain herding cats Jul 2014 #39
Big fear is if Ebola mutates from bodily contact to airborne infection. Divernan Jul 2014 #4
How likely is that to happen? Hugabear Jul 2014 #43
For ebola, possible but not likely; HIV is a different story. Divernan Jul 2014 #45
Monclonal antibodies taken from survivors could provide vaccinations for strain variants. DhhD Jul 2014 #10
I highly suggest the book Spillover Marrah_G Jul 2014 #28
Thanks for that title... ReRe Jul 2014 #33
Not weird! It is one of my interests also! :) nt Mojorabbit Jul 2014 #47
Relatively long incubation and ease of airtravel make this very scary. McCamy Taylor Jul 2014 #35
on the bright side, eShirl Jul 2014 #36
The part I found most alarming Aerows Jul 2014 #51
Serious stuff. An average of 20 new *reported* cases per day between 6/24 and 7/23. Zorra Jul 2014 #37
As if Ebola, MERS, SARS and Biological Hazards of Unkown Origins...... DeSwiss Jul 2014 #41
Horrible news! Aerows Jul 2014 #48
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