then I assume you know all about the Scientific Revolution of the 16th and 17th centuries. The history of math, astronomy, and physics during this period is dominated by Copernicus, Brahe, Kepler, Galileo, Descartes, Leibniz, Newton, and perhaps a few others. I will skip the revolution in anatomy, physiology, and medicine, which happened at roughly the same time, partly because I don't know much about these fields, but mainly because they have nothing to do with math or astronomy (unless you believe in the scientific method, which I don't.) Note that I left Francis Bacon off the list.
If you want dirt, you can dig up an unfounded assertion by a couple of journalists to the effect that Kepler murdered Brahe. (No reputable historian of science takes such charges seriously.) What's true is that Brahe and Kepler met in Prague, and that meeting led to Kepler's laws of planetary motion.
If you visit Prague, you will want to see this statue, and you can also see Tycho's grave in the Tyn church (which itself has an interesting history).
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