University of Florida College of Pharmacy reveals breakthrough cancer drug [View all]
Researchers from the University of Florida College of Pharmacy say they have discovered a safer and more effective anticancer drug. The new treatment would target leukemia, lymphoma, and breast and lung cancers.
The drug, known currently as DT2216, affects a protein (called B-cell lymphoma-extra large), which grows malignant cells and strengthens their resistance to treatment.
There's already an inhibitor drug, but it causes a drop in blood platelets, raising the risk of bleeding. This led the U.S. Food and Drug Administration to deny approval for the earlier drug. Since then, scientists have been seeking an alternative.
According to a release on UF's website, the new drug works better against a variety of tumor cells aided by the BCL-XL protein, and is also less toxic to blood platelets. University researchers developed the new BCL-XL-targeting anticancer drug using a technology that relies on small molecules that suppress and break down cancer-promoting proteins. They published their findings in the journal Nature Medicine on Dec. 2.
Read more: https://www.orlandoweekly.com/Blogs/archives/2019/12/12/university-of-florida-college-of-pharmacy-reveals-breakthrough-cancer-drug
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