Brazilian chloroquine study halted after high dose proved lethal for some patients

[abqtommy]

1. Chloroquine has a long history of use in malaria infections. In doing some research I found that

in some cases contracting malaria and undergoing treatment heart problems appeared after some
years had passed, but no immediate health concerns with using chloroquine itself. Wouldn't it be
wise to use malaria treatment dosage levels since those are already established?* In the information
I saw, hydrocholoroquine was not listed as a treatment for malaria although it is used to treat lupus.

*https://www.drugs.com/dosage/chloroquine.html#Usual_Adult_Dose_for_Malaria_Prophylaxis

"Usual Adult Dose for Malaria Prophylaxis

500 mg chloroquine phosphate (300 mg base) orally on the same day each week

Comments:
-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart.
-Suppressive therapy should continue for 8 weeks after leaving the endemic area.

Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum

CDC Recommendations:
300 mg base (500 mg salt) orally once a week"

Interesting in that this dosage is a preventative and after the first "loading dose" the medication is
taken only once a week...