1) Because of the ways drugs are regulated, even if you don't belong to Costco or Sam's Club, you can still get prescriptions there at a discount. A lot of workers, even some managers, don't know this.
2) Talk to the pharmacist, he may make some suggestions.
3) There are a lot of discussion boards about particular ailments and treatments, try searching for "leprosy message board" (or whatever ailment you have)
4) Try searching The People's Pharmacy http://www.peoplespharmacy.com/
which is run by a pharmacologist-anthropologist couple: http://www.peoplespharmacy.com/about/
5) There used to be websites which would search for the best price, including from Canada or Mexico mail-order.
Don't know if they're still out there.
6) Doctor gave me a prescription, said it was really cheap, about 10 bucks. First pharmacy told me it was over $100. Went to a different pharmacy, they told me it was $15. So ask your doctor if it's really supposed to be that expensive, I don't know if the first pharmacist misread the prescription or what.
7) Sometimes the drug mfgrs give samples to doctors free. Ask if he can get you samples.
8) Also most mfgrs have programs where they provide drugs cheap if you're poor. Here's one link I just googled up: http://www.rxassist.org/default.cfm
Here's another: http://www.needymeds.org/
9) Target has lots of generics for $4: http://sites.target.com/site/en/spot/page.jsp?title=pharmacy_generics&ref=nav_phrm_1_3
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