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hlthe2b

(112,687 posts)
5. Always encouraging. One preliminary caution though, these studies most often enroll confirmed AD patients
Mon Dec 29, 2025, 10:25 AM
9 hrs ago

and non-AD control comparisons with very strict exclusion criteria so as to avoid confounding factors, like cerebral vascular disease, moderate to severe cardiac insufficiency or other chronic health conditions that likewise influence brain function and thus response to NAD+ in their study. While a healthy population (especially those with early onset Alzheimer's) is out there and likewise in need of interventions, it may be difficult to extrapolate these findings--even with further validation--to the majority of AD patients (or those identified to be most at risk), depending on how well and how early their concomitant additional health issues are identified and treated.

Still, a positive development that bears watching once human studies become available (while taking the qualifiers above into account).

Recommendations

5 members have recommended this reply (displayed in chronological order):

So after all this time, nutritional supplements are available hiding in plain sight bucolic_frolic 9 hrs ago #1
This study uses a drug, P7C3-A20 KLK1972 9 hrs ago #3
So this means COL Mustard 6 hrs ago #23
So How Do We Regenerate NDA+ Rendville 9 hrs ago #2
Exercise is the best method KLK1972 9 hrs ago #7
How much exercise and what kind? Irish_Dem 8 hrs ago #10
Okay ananda 7 hrs ago #21
Maybe both weight lifting and cardio create the NDA? Irish_Dem 6 hrs ago #26
Maybe ananda 5 hrs ago #30
Yes. And if it loads on anti-dementia, all the better. Irish_Dem 5 hrs ago #31
with supplements - Nigrum Cattus 8 hrs ago #8
One study of mice does not equal a cure for humans Fiendish Thingy 9 hrs ago #4
Yes... with my qualifiers below... hlthe2b 9 hrs ago #6
Remarkable claims of a cure need to be backed up by remarkable evidence. Any breakthrough is welcome, even if it Martin68 7 hrs ago #13
Yes! Not that this isn't very interesting, and fully deserving of discussion stopdiggin 7 hrs ago #19
Always encouraging. One preliminary caution though, these studies most often enroll confirmed AD patients hlthe2b 9 hrs ago #5
Click-bait headline. TheRickles 8 hrs ago #9
So the dead brain cells grow back? Progressive dog 8 hrs ago #11
Who knows.. I remember that when a nerve was cut, like in an accident, that it would never - ever reconnect. That LiberalArkie 7 hrs ago #12
Creatine being studied now GreatGazoo 7 hrs ago #14
I have some but forget to take it multigraincracker 7 hrs ago #17
I started it 3 months ago for better sleep GreatGazoo 7 hrs ago #20
What kind? Sleep is one thing I really miss. LiberalArkie 5 hrs ago #33
For me the effect was better quality of sleep GreatGazoo 1 hr ago #35
Thank you, I will order some and give it a whirl.. LiberalArkie 1 hr ago #36
"nearly statistically significant" equals "not significant". Sorry - maybe someday, but not yet. TheRickles 6 hrs ago #25
Encouraging! Sogo 7 hrs ago #15
Time for RFK jr to step in and stop this witchcraft! progressoid 7 hrs ago #16
There's no better time in history to be a mouse! tinrobot 7 hrs ago #18
Promising early days snowybirdie 7 hrs ago #22
TikTok scammers will run with this wolfie001 6 hrs ago #24
In almost every case, these "breakthrough" posts raise false hopes. This is true for almost every University news... NNadir 6 hrs ago #27
RFK Jr doesn't want people living longer. Irish_Dem 6 hrs ago #28
Three to five years from Type one diabetes cure since 1987....When my 6yr old's test was positive. IA8IT 5 hrs ago #29
If this story were true it would be all over every news service in the world. So yes - I'm skeptical. flashman13 5 hrs ago #32
LiberalArkie .......... Upthevibe 5 hrs ago #34
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