Welcome to DU! The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards. Join the community: Create a free account Support DU (and get rid of ads!): Become a Star Member Latest Breaking News Editorials & Other Articles General Discussion The DU Lounge All Forums Issue Forums Culture Forums Alliance Forums Region Forums Support Forums Help & Search

NNadir

(37,235 posts)
27. In almost every case, these "breakthrough" posts raise false hopes. This is true for almost every University news...
Mon Dec 29, 2025, 01:15 PM
4 hrs ago

...release, notably in medicine, but widely found with respect to energy "breakthroughs."

Alzheimer's is a very tragic disease, and regrettably, its history is littered with scientific announcements of "breakthroughs" that have not panned out.

In at least one case - and I'm not implying this is the case here - a "breakthrough" was found to consist entirely of scientific fraud.

It is very difficult to ascertain what behaviors in a mouse display "full recovery."

I covered this case elsewhere here; books have been written on it.

Some remarks on purported fraud concerned with αβ oligomer hypothesis in Alzheimer's research.

There has been some criticism of the tone of Charles Piller's article in Science, as well as his book expanding on the article, Doctored Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's

Criticism by an Alzheimer's researcher of Piller's book and claims can be found here: Fraud, arrogance, and tragedy: the case of Doctored

Alzheimer's is a terrible and generally intractable disease; as a scientist, I certainly applaud research. I am too old though, and have lived too long, to jump up and down with joy every time a "breakthrough" is announced. I have worked for much of my life in support of drug development and am aware of pitfalls - huge pitfalls - that occur along the way to medical treatments. This is not to say that some them don't work; obviously they do, but the road is long, painful, and littered with failure.

Recommendations

0 members have recommended this reply (displayed in chronological order):

So after all this time, nutritional supplements are available hiding in plain sight bucolic_frolic 8 hrs ago #1
This study uses a drug, P7C3-A20 KLK1972 7 hrs ago #3
So this means COL Mustard 5 hrs ago #23
So How Do We Regenerate NDA+ Rendville 7 hrs ago #2
Exercise is the best method KLK1972 7 hrs ago #7
How much exercise and what kind? Irish_Dem 6 hrs ago #10
Okay ananda 5 hrs ago #21
Maybe both weight lifting and cardio create the NDA? Irish_Dem 4 hrs ago #26
Maybe ananda 4 hrs ago #30
Yes. And if it loads on anti-dementia, all the better. Irish_Dem 4 hrs ago #31
with supplements - Nigrum Cattus 6 hrs ago #8
One study of mice does not equal a cure for humans Fiendish Thingy 7 hrs ago #4
Yes... with my qualifiers below... hlthe2b 7 hrs ago #6
Remarkable claims of a cure need to be backed up by remarkable evidence. Any breakthrough is welcome, even if it Martin68 6 hrs ago #13
Yes! Not that this isn't very interesting, and fully deserving of discussion stopdiggin 5 hrs ago #19
Always encouraging. One preliminary caution though, these studies most often enroll confirmed AD patients hlthe2b 7 hrs ago #5
Click-bait headline. TheRickles 6 hrs ago #9
So the dead brain cells grow back? Progressive dog 6 hrs ago #11
Who knows.. I remember that when a nerve was cut, like in an accident, that it would never - ever reconnect. That LiberalArkie 6 hrs ago #12
Creatine being studied now GreatGazoo 6 hrs ago #14
I have some but forget to take it multigraincracker 6 hrs ago #17
I started it 3 months ago for better sleep GreatGazoo 5 hrs ago #20
What kind? Sleep is one thing I really miss. LiberalArkie 3 hrs ago #33
For me the effect was better quality of sleep GreatGazoo 7 min ago #35
Thank you, I will order some and give it a whirl.. LiberalArkie 2 min ago #36
"nearly statistically significant" equals "not significant". Sorry - maybe someday, but not yet. TheRickles 5 hrs ago #25
Encouraging! Sogo 6 hrs ago #15
Time for RFK jr to step in and stop this witchcraft! progressoid 6 hrs ago #16
There's no better time in history to be a mouse! tinrobot 5 hrs ago #18
Promising early days snowybirdie 5 hrs ago #22
TikTok scammers will run with this wolfie001 5 hrs ago #24
In almost every case, these "breakthrough" posts raise false hopes. This is true for almost every University news... NNadir 4 hrs ago #27
RFK Jr doesn't want people living longer. Irish_Dem 4 hrs ago #28
Three to five years from Type one diabetes cure since 1987....When my 6yr old's test was positive. IA8IT 4 hrs ago #29
If this story were true it would be all over every news service in the world. So yes - I'm skeptical. flashman13 3 hrs ago #32
LiberalArkie .......... Upthevibe 3 hrs ago #34
Latest Discussions»Issue Forums»Health»New study shows Alzheimer...»Reply #27