Fun With Poverty: The Immunology of How Cockroaches Make People Sick.

[NNadir]

3. I don't know, but I can point out that the authors of this paper are from Thailand.

From my somewhat limited understanding, there is an interplay of factors involved in immunological responses, some of which are genetic, and define the "Tregitopes" with which people are born.

It may be that people living in tropical areas may have more "tregitopes" that either moderate or conversely, sensitize people to cockroach allergens.

While natural selection may play a role in the survival of anti-vax Floridians by killing a lot of them off, it is possible that the descendants of the survivors - there will be some, some of whom will be at procreative age - may record the exposure to Covid in their genome in a statistical sense: Some may have epitopes favoring their survival already, perhaps from SARS exposures many generations ago, and those that do, will be those who leave the signature in their children, enriching the population, as those who lack the gene are less likely to survive, and thus less likely to have children.

To your point, it would be interesting to study Polynesian populations to understand their immune reaction to cockroaches. To my knowledge, it hasn't been done.