Origins of the Irish down to mass migration, ancient DNA confirms [View all]
Scientists from Dublin and Belfast have looked deep into Irelands early history to discover a still-familiar pattern of migration: of stone age settlers with origins in the Fertile Crescent, and bronze age economic migrants who began a journey somewhere in eastern Europe.
The evidence has lain for more than 5,000 years in the bones of a woman farmer unearthed from a tomb in Ballynahatty, near Belfast, and in the remains of three men who lived between 3,000 and 4,000 years ago and were buried on Rathlin Island in County Antrim.
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The ancestors of the Stone Age farmers began their journey in the Bible lands, where agriculture first began, and arrived in Ireland perhaps via the southern Mediterranean. They brought with them cattle, cereals, ceramics and a tendency to black hair and brown eyes.
These settlers were followed by people, initially from the Pontic steppe of southern Russia, who knew how to mine for copper and work with gold, and who carried the genetic variant for a blood disorder called haemochromatosis, a hereditary genetic condition so common in Ireland that it is sometimes called Celtic disease.
http://www.theguardian.com/science/2015/dec/28/origins-of-the-irish-down-to-mass-migration-ancient-dna-confirms
The Neolithic and Bronze Age transitions were profound cultural shifts catalyzed in parts of Europe by migrations, first of early farmers from the Near East and then Bronze Age herders from the Pontic Steppe. However, a decades-long, unresolved controversy is whether population change or cultural adoption occurred at the Atlantic edge, within the British Isles. We address this issue by using the first whole genome data from prehistoric Irish individuals. A Neolithic woman (33433020 cal BC) from a megalithic burial (10.3× coverage) possessed a genome of predominantly Near Eastern origin. She had some huntergatherer ancestry but belonged to a population of large effective size, suggesting a substantial influx of early farmers to the island. Three Bronze Age individuals from Rathlin Island (20261534 cal BC), including one high coverage (10.5×) genome, showed substantial Steppe genetic heritage indicating that the European population upheavals of the third millennium manifested all of the way from southern Siberia to the western ocean. This turnover invites the possibility of accompanying introduction of Indo-European, perhaps early Celtic, language. Irish Bronze Age haplotypic similarity is strongest within modern Irish, Scottish, and Welsh populations, and several important genetic variants that today show maximal or very high frequencies in Ireland appear at this horizon. These include those coding for lactase persistence, blue eye color, Y chromosome R1b haplotypes, and the hemochromatosis C282Y allele; to our knowledge, the first detection of a known Mendelian disease variant in prehistory. These findings together suggest the establishment of central attributes of the Irish genome 4,000 y ago.
http://www.pnas.org/content/early/2015/12/22/1518445113